Khat: pharmacological and medical aspects and its social use in Yemen
@article{AlMotarreb2002KhatPA, title={Khat: pharmacological and medical aspects and its social use in Yemen}, author={Ahmed Al‐Motarreb and Kathryn Baker and Kenneth J. Broadley}, journal={Phytotherapy Research}, year={2002}, volume={16} }
Fresh leaves of the khat tree (Catha edulis Forsk.) are chewed for their euphoric properties in East Africa and parts of the Middle East, such as The Yemen. This review describes the history, cultivation and constituents of khat, and the social aspects of khat chewing in Yemen. The major pharmacologically active constituent of the fresh leaves is (−)‐S‐cathinone. The pharmacology of (−)‐S‐cathinone in the central nervous system and the peripheral effects are described. (−)‐S‐Cathinone is…
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