Key nodes of a microRNA network associated with the integrated mesenchymal subtype of high-grade serous ovarian cancer

@inproceedings{Sun2015KeyNO,
  title={Key nodes of a microRNA network associated with the integrated mesenchymal subtype of high-grade serous ovarian cancer},
  author={Yan Sun and Fei Yun Guo and Marina Bagnoli and Feng-xia Xue and Baocun Sun and Ilya Shmulevich and Delia Mezzanzanica and Ke-xin Chen and Anil Sood and Da Som Yang and Wei Zhang},
  booktitle={Chinese journal of cancer},
  year={2015}
}
Metastasis is the main cause of cancer mortality. One of the initiating events of cancer metastasis of epithelial tumors is epithelial-to-mesenchymal transition (EMT), during which cells dedifferentiate from a relatively rigid cell structure/morphology to a flexible and changeable structure/morphology often associated with mesenchymal cells. The presence of EMT in human epithelial tumors is reflected by the increased expression of genes and levels of proteins that are preferentially present in… CONTINUE READING
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Ovarian cancer: a molecularly insidious disease

Chinese journal of cancer • 2015
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