Key issues in contemporary behavioral genetics

  title={Key issues in contemporary behavioral genetics},
  author={Wim E Crusio},
  journal={Current Opinion in Behavioral Sciences},
  • Wim E Crusio
  • Published 1 April 2015
  • Psychology, Biology
  • Current Opinion in Behavioral Sciences
Reproducibility and replicability of rodent phenotyping in preclinical studies
Treatment Approaches in Rodent Models for Autism Spectrum Disorder.
A critical overview of the most relevant advances in designing treatments for ASD, focusing on the most commonly used animal model, the laboratory mouse, and highlights the theoretical and methodological approaches that seem more promising.
The genetic basis of animal behavioural diversity in natural populations
The findings show that despite widespread accessibility of molecular approaches given current sequencing technologies, efforts to elucidate the genetic basis of behaviour in free‐ranging systems has been limited to relatively few species.
Behavioral and Brain Functions at 15
  • Wim E Crusio
  • Psychology
    Behavioral and brain functions : BBF
  • 2020
Behavioral and Brain Functions was the first behavioral neuroscience journal that was online-only and open-access (OA) and has established itself as a well-respected voice in the field, publishing a variety of high-quality articles that are regularly cited in other journals, as shown by its solid current impact factor.


The genetics of behavior
The Genetics of Behavior by Lee Ehrman and Peter Parsons concerns a topic of rising interest among biologists, psychologists, anthropologists, and others particularly because of issues concerning
This chapter provides a brief overview of quantitative-genetic theory, which provides important tools to help elucidate the genetic underpinnings of behavioral and neural phenotypes, as well as into brain-behavior relationships.
History of Behavior Genetics
This chapter considers both the long past and some aspects of the short history of behavior genetics, the recognition since antiquity that behavioral traits are in part inherited, and the controversy concerning the extent to which this is so, a discussion often going under the label of the nature–nurture controversy.
What's Wrong With My Mouse?: Behavioral Phenotyping of Transgenic and Knockout Mice
Three groups recently independently produced null mutant mice for the corticotropinreleasing hormone 2 receptor, and three different results were reported: one group found a tendency for greater anxiety in null mutants of both sexes; one found significantly greater anxietyIn null mutants; and the third found that null mutant males (but not females) spent significantly more time in the center of the field, but interpreted the result to indicate greater anxiety.
Stability of inbred mouse strain differences in behavior and brain size between laboratories and across decades
When a wide range of phenotypes is considered, no inbred strain appears to be exceptionally stable or labile across laboratories in any general sense, and there is no tendency to observe higher correlations among studies done more recently.
Genetics of mouse behavior: interactions with laboratory environment.
Strains of mice that show characteristic patterns of behavior are critical for research in neurobehavioral genetics and experiments characterizing mutants may yield results that are idiosyncratic to a particular laboratory.
Assessing antidepressant activity in rodents: recent developments and future needs.
Huntington's disease
Proceedings of the Australian Neuroscience Society Symposium: Schizophrenia MOLECULAR GENETICS OF SCHIZOPHRENIA
Evidence from family, twin and adoption studies clearly demonstrates that schizophrenia aggregates in families, with this clustering largely attributable to genetic rather than cultural or environmental factors.