Key genes and pathways predicted in papillary thyroid carcinoma based on bioinformatics analysis

@article{Yu2016KeyGA,
  title={Key genes and pathways predicted in papillary thyroid carcinoma based on bioinformatics analysis},
  author={Jing Yu and Weihua Mai and Yinghua Cui and Lingshun Kong},
  journal={Journal of Endocrinological Investigation},
  year={2016},
  volume={39},
  pages={1285-1293}
}
PurposeThe aim of this study was to predict the key genes and pathways associated with papillary thyroid carcinoma (PTC).MethodsBased on the microarray data of GSE3467 from Gene Expression Omnibus database, we identified the differentially expressed genes (DEGs) between 9 PTC samples and 9 normal controls. With the identified DEGs, functional enrichment analyses were performed. Additionally, a protein–protein interaction network was constructed to screened out some key gene nodes. These key… CONTINUE READING
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