Key features of cereal genome organization as revealed by the use of cytosine methylation-sensitive restriction endonucleases.

@article{Moore1993KeyFO,
  title={Key features of cereal genome organization as revealed by the use of cytosine methylation-sensitive restriction endonucleases.},
  author={Graham Moore and Shahal Abbo and Wing-tai Cheung and Tracie N. Foote and Mike Gale and Robert Max David Koebner and Andrea L Leitch and Ian Leitch and Tracy Money and Patrick R Stancombe},
  journal={Genomics},
  year={1993},
  volume={15 3},
  pages={
          472-82
        }
}
Unlike mammalian genomes, cereal (Gramineae) genomes exhibit little suppression of CpG dinucleotides. In cereal genomes, however, most of the numerous potential recognition sites for CpG methylation-sensitive restriction enzymes are methylated. Analysis of cereal genomic libraries and of regions flanking genes indicates that unmethylated NotI sites are useful landmarks for regions containing genes/single-copy sequences. Studies of a rye chromosome arm indicate that its pericentromeric region… CONTINUE READING
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