Key Articles of Dietary Interventions that Influence Cardiovascular Mortality

  title={Key Articles of Dietary Interventions that Influence Cardiovascular Mortality},
  author={Shannon W Finks and Anita Airee and Sheryl L. Chow and Tracy E. Macaulay and Michael P. Moranville and Kelly C. Rogers and Toby C. Trujillo},
  journal={Pharmacotherapy: The Journal of Human Pharmacology and Drug Therapy},
Lifestyle modifications, particularly diet, are a key component to the reduction of cardiovascular events. Diets high in carbohydrates and saturated fat have been shown to negatively affect blood cholesterol, thereby increasing the risk for cardiovascular disease (CVD). Dietary interventions that emphasize the consumption of whole grains, fruits, and vegetables have been shown to be successful in reducing cardiovascular risk. Clinical pharmacist practitioners need to be knowledgeable regarding… 

Nutraceuticals with lipid-lowering activity: do they have any effect beyond cholesterol reduction?

No evidence is available that demonstrates a preventive effect of lipid-lowering nutraceuticals on hard cardiovascular outcomes, but for berberine and soluble fibers, the evidence of a positive multimetabolic effect is growing, contributing to a better control of both glucose and lipids values that consequently could be useful in the management of metabolic syndrome.

The Health Potential of Fruits and Vegetables Phytochemicals: Notable Examples

D diets rich in fruits and vegetables in combination with medical therapies are being considered as novel approaches to treatment, since some phytochemicals regulate the same genes and pathways targeted by drugs, and might be a promising tool for the prevention and/or amelioration of a wide range of diseases.

Effects of high phenolic olive oil on cardiovascular risk factors: A systematic review and meta-analysis.

Predicting effective factors on eating behaviors in the prevention of cardiovascular disease based on the PRECEDE model

According to the results of this study, self-efficacy, attitude, and enabling factors were the main predicting factors for eating behaviors; therefore, to prevent cardiovascular disease and enhance healthy eating behavior, it is recommended to change attitude and enhance self- efficacy and enabling Factors in the community.

Comparison of the effect of omega-3 supplements and fresh fish on lipid profile: a randomized, open-labeled trial

Consumption of fresh fish seems to be superior in positively modifying the lipid profiles which may have important translations in the occurrence of cardiovascular events.

Assessment of Cardiovascular Diseases & Drug Therapy in Northern and Southern Parts of Bangladesh

The most frequently reported diseases were myocardial infarction, unstable angina (UA), hypertension (HTN), and stroke, and the most prescribed drugs were diuretics and β-blockers.


The prevalence of CVDs with drug utilization and current trends in Bangladesh and the most frequently prescribed drugs may be propitious for the general physicians for optimizing rational use of cardiovascular drugs and also accessible in formulating strategy for effective cardiovascular disease management.

Serum Fetuin-A Levels in Patients with Cardiovascular Disease: A Meta-Analysis

The data indicated that decreased serum FA level is correlated with the development of CVDs, and FA might be clinically valuable for reflecting the progression ofCVDs.

Inverse association between docosahexaenoic acid and mortality in patients on hemodialysis during over 10 years

The level of DHA in RBCs could be an independent predictor of all‐cause mortality in HD patients even during a long period of follow‐up.



The combination of high fruit and vegetable and low saturated fat intakes is more protective against mortality in aging men than is either alone: the Baltimore Longitudinal Study of Aging.

The results confirm the protective effects of low SF and high FV intake against CHD mortality and demonstrate that the combination of both behaviors is more protective than either alone, suggesting that their beneficial effects are mediated by different mechanisms.

Effect of diet intervention on long‐term mortality in healthy middle‐aged men with combined hyperlipidaemia

Objectives.  The aim was to study the effect of a 5‐year diet intervention on 24‐year mortality in middle aged men with combined hyperlipidaemia.