Ketotifen inhibits exacerbation of allergic airway hyperreactivity by racemic salbutamol in the guinea pig.

@article{Hoshiko1993KetotifenIE,
  title={Ketotifen inhibits exacerbation of allergic airway hyperreactivity by racemic salbutamol in the guinea pig.},
  author={K. Hoshiko and A. Kristersson and J. Morley},
  journal={The Journal of allergy and clinical immunology},
  year={1993},
  volume={91 4},
  pages={
          909-16
        }
}
  • K. Hoshiko, A. Kristersson, J. Morley
  • Published 1993
  • Medicine
  • The Journal of allergy and clinical immunology
  • In passively sensitized anesthetized guinea pigs, intravenous infusion of low doses of antigen ovalbumin induced a marked increased responsivity of the airways to intravenous injection of leukotriene C4. Sustained infusion of racemic salbutamol intensified responses to leukotriene C4 both before and after infusion of ovalbumin. Hyperreactivity as a result of infusion of ovalbumin was inhibited by intraduodenal injection of either hydrocortisone or ketotifen at doses that did not diminish… CONTINUE READING

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    References

    Publications referenced by this paper.
    SHOWING 1-10 OF 17 REFERENCES
    Ketotifen and asthma.
    • 16
    • PDF
    Asthma induced by adrenergic aerosols.
    • 103