Ketotifen in adult asthma.


The efficacy and adverse effects of ketotifen 1 mg twice daily and 2 mg twice daily were compared with placebo in 50 patients with atopic asthma in a multicentre, double-blind study. Ketotifen in the higher dosage caused a slight reduction in salbutamol usage and a modest improvement in breathing in patients not already receiving inhaled corticosteroids. The drug was ineffective in patients receiving inhaled corticosteroids. Drowsiness was a troublesome effect causing withdrawal from treatment or reduction of dosage in seven patients while receiving ketotifen compared with only three while receiving placebo.


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@article{Dyson1980KetotifenIA, title={Ketotifen in adult asthma.}, author={Anthony J. Dyson and Amy D MacKay}, journal={British medical journal}, year={1980}, volume={280 6217}, pages={862} }