Ketorolac tromethamine formulations: an overview

  title={Ketorolac tromethamine formulations: an overview},
  author={V. Sinha and R. Kumar and G. Singh},
  journal={Expert Opinion on Drug Delivery},
  pages={961 - 975}
  • V. Sinha, R. Kumar, G. Singh
  • Published 2009
  • Medicine
  • Expert Opinion on Drug Delivery
  • Ketorolac tromethamine (KT) is a non-steroidal anti-inflammatory drug that belongs to the class of heteroaryl acetic acid derivatives. It is a non-selective cyclooxygenase (COX) inhibitor, being marketed in the racemate form. Most of its analgesic and COX inhibitory activity is retained in the S-isomer. Ketorolac is administered as its tromethamine salt orally, intramuscularly, intravenously and as a topical ophthalmic solution. The frequent occurrence of gastrointestinal disturbances including… CONTINUE READING


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