Ketorolac eye drops reduce inflammation and delay re-epithelization in response to corneal alkali burn in rabbits, without affecting iNOS or MMP-9.

@article{Lima2015KetorolacED,
  title={Ketorolac eye drops reduce inflammation and delay re-epithelization in response to corneal alkali burn in rabbits, without affecting iNOS or MMP-9.},
  author={Tiago Barbalho Lima and Alexandre Pinto Ribeiro and Luciano Fernandes da Conceiç{\~a}o and M{\'a}rcio de Barros Bandarra and Wilson G{\'o}mez Manrique and Jos{\'e} Luiz Laus},
  journal={Arquivos brasileiros de oftalmologia},
  year={2015},
  volume={78 2},
  pages={
          67-72
        }
}
PURPOSES To assess the effects of 0.5% ketorolac tromethamine without preservatives on the expression of iNOS and MMP-9 in alkali burn ulcers. METHODS Twelve eyes of 120-day-old male rabbits were treated (TG) every 6 h with 0.5% ketorolac tromethamine and 12 other eyes were treated with saline solution (CG), immediately after the occurrence of ulcers by 1 M sodium hydroxide (NaOH). Re-epithelialization was monitored using fluorescein every 6 h. After 24 h, six corneas (n=6) of each group were… CONTINUE READING

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