Ketonic intermediates in the demethylation of lanosterol.

  title={Ketonic intermediates in the demethylation of lanosterol.},
  author={Martin Lindberg and F GAUTSCHI and Konrad Bloch},
  journal={The Journal of biological chemistry},
The isolation and identification of 4, 4-dimethyl-Ass %holestadienol (14-desmethyllanosterol), an early intermediate in the biological conversion of lanosterol to cholesterol, has been described in earlier reports from this laboratory (l-3). Further studies with 4,4-dimethylcholestane derivatives have shown that 4,4-dimethylds-cholestenol (14-desmethyl24,25… CONTINUE READING