Ketone infusion lowers hormonal responses to hypoglycaemia: evidence for acute cerebral utilization of a non-glucose fuel.

@article{Amiel1991KetoneIL,
  title={Ketone infusion lowers hormonal responses to hypoglycaemia: evidence for acute cerebral utilization of a non-glucose fuel.},
  author={Stephanie A. Amiel and H{\'e}l{\`e}ne Archibald and G. D. Chusney and A J Williams and Edwin A. M. Gale},
  journal={Clinical science},
  year={1991},
  volume={81 2},
  pages={189-94}
}
1. The effect of hyperketonaemia on counter-regulatory hormone responses to hypoglycaemia has been examined in six healthy subjects. 2. A controlled, step-wise reduction in blood glucose concentration was achieved by adjusting the rate of glucose infusion during a primed-continuous infusion of soluble insulin (1.5 m-units min-1 kg-1 body weight, plasma insulin concentration approximately 90 m-units/l). Simultaneous infusion of either saline or beta-hydroxybutyrate (3 mg min-1 kg-1 body weight… CONTINUE READING

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