Ketone body production is differentially altered in steatosis and non-alcoholic steatohepatitis in obese humans.

@article{Mnnist2015KetoneBP,
  title={Ketone body production is differentially altered in steatosis and non-alcoholic steatohepatitis in obese humans.},
  author={Ville T M{\"a}nnist{\"o} and Marko Simonen and Jenni Hyysalo and Pasi Soininen and Antti J. Kangas and Dorota Kaminska and Ananda K Matte and Sari Venesmaa and Pirjo K{\"a}kel{\"a} and Vesa K{\"a}rj{\"a} and Johanna Arola and H Gylling and Henna Cederberg and Johanna Kuusisto and Markku Laakso and Hannele Yki-J{\"a}rvinen and Mika Ala-Korpela and Jussi Pihlajam{\"a}ki},
  journal={Liver international : official journal of the International Association for the Study of the Liver},
  year={2015},
  volume={35 7},
  pages={
          1853-61
        }
}
BACKGROUND & AIMS Levels of ketone bodies have been reported to be both increased and decreased in individuals with non-alcoholic fatty liver disease. We investigated whether the metabolism of ketone bodies is different in simple steatosis and in non-alcoholic steatohepatitis (NASH). METHODS Serum low molecular weight molecules including ketone bodies were measured using high-throughput proton (1H) nuclear magnetic resonance in 116 (76 categorized unequivocally to those with normal liver… CONTINUE READING
1
Twitter Mention

Citations

Publications citing this paper.
SHOWING 1-10 OF 13 CITATIONS

Fatty acid metabolism is altered in non-alcoholic steatohepatitis independent of obesity.

  • Metabolism: clinical and experimental
  • 2016
VIEW 4 EXCERPTS
CITES BACKGROUND & METHODS

Emmi Lyyra ( née Suomela ) DETERMINANTS OF FATTY LIVER FROM CHILDHOOD TO ADULTHOOD The Cardiovascular Risk in Young Finns Study

TO ADULTHOOD, Emmi Lyyra née Suomela, Emmi Lyyra, née Suomela, Olli T. Raitakari
  • 2019

References

Publications referenced by this paper.
SHOWING 1-10 OF 43 REFERENCES

Hyperglycemia and a common variant of GCKR are associated with Liver International

A Stancakova, M Civelek, NK Saleem
  • Diabetes
  • 2014
VIEW 10 EXCERPTS
HIGHLY INFLUENTIAL

A populationbased study on the prevalence of NASH using scores validated against liver histology

J Hyysalo, VT M€annist€ o, Y Zhou
  • J Hepatol
  • 2013
VIEW 8 EXCERPTS
HIGHLY INFLUENTIAL