Ketone body production and disposal: effects of fasting, diabetes, and exercise.

@article{Balasse1989KetoneBP,
  title={Ketone body production and disposal: effects of fasting, diabetes, and exercise.},
  author={Edmond O Balasse and Françoise F{\'e}ry},
  journal={Diabetes/metabolism reviews},
  year={1989},
  volume={5 3},
  pages={247-70}
}
Turnover studies performed during progressive fasting in normal subjects indicate that the production rate and the concentration of KB rise markedly during the early phase of fasting and start reaching a plateau after about 5 days. In addition to increased production, a reduction in the metabolic clearance rate of KB contributes to the hyperketonemia. This reduced metabolic clearance rate reflects essentially the progressive saturation of muscular ketone uptake that occurs with increasing… CONTINUE READING
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