Ketogenic dietary therapies in adults with epilepsy: a practical guide

@article{Schoeler2016KetogenicDT,
  title={Ketogenic dietary therapies in adults with epilepsy: a practical guide},
  author={N. Schoeler and J. H. Cross},
  journal={Practical Neurology},
  year={2016},
  volume={16},
  pages={208 - 214}
}
Ketogenic dietary therapies are an effective treatment option for children with drug-resistant epilepsy. There is an increasing worldwide interest in using these diets to manage adult epilepsy; uncontrolled studies show similar response rates to those in children. Despite this, there are only a few centres with dedicated services for adults. We clearly need controlled studies of this treatment in adults. Here, we aim to familiarise adult neurologists with the evidence base for these diets and… Expand

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References

SHOWING 1-10 OF 49 REFERENCES
Dietary treatment of epilepsy: practical implementation of ketogenic therapy.
TLDR
Dietary treatments for epilepsy include the traditional ketogenic diets but also the newer modified Atkins diet and low glycaemic index treatment. Expand
Worldwide Dietary Therapies for Adults With Epilepsy and Other Disorders
TLDR
The session provided evidence that dietary therapies are safe and effective in adults and demonstrated not only in patients with epilepsy but also patients with propriospinal myoclonus, astrocytoma, type 2 diabetes, obesity, hyperlipidemia, and metabolic disorder. Expand
Ketogenic dietary therapies for adults with epilepsy: Feasibility and classification of response
TLDR
It is suggested that adults with epilepsy are able to follow ketogenic dietary therapies long-term, and such treatment can lead to seizure reduction. Expand
Can we predict a favourable response to Ketogenic Diet Therapies for drug-resistant epilepsy?
TLDR
No strong evidence that there are any specific factors that affect response to Ketogenic Dietary Therapies is found; gender and intellectual status do not seem to affect response; evidence is inconsistent for all other factors. Expand
The Ketogenic Diet for Intractable Epilepsy in Adults: Preliminary Results
TLDR
Preliminary results in 11 adults prospectively treated with the ketogenic diet who had previously failed to gain seizure control with two or more medications and/or surgery are reported. Expand
Dietary treatment in adults with refractory epilepsy
TLDR
KD and MAD treatment of refractory epilepsy in adults show modest efficacy, although in some patients the effect is remarkable, and the diets are well-tolerated, but often discontinued because of their restrictiveness. Expand
Efficacy and tolerability of the Modified Atkins Diet in adults with pharmacoresistant epilepsy: A prospective observational study
Purpose:  Evidence from the pediatric population exists for the efficacy of ketogenic diets in reducing seizure frequency in patients with intractable epilepsy. Recent evidence suggests that aExpand
Is the ketogenic diet effective in specific epilepsy syndromes?
TLDR
The effectiveness of the ketogenic diet in Dravet syndrome, epilepsy with myoclonic-atonic seizures, mitochondrial disease, tuberous sclerosis, late infantile and juvenile neuronal ceroid lipofuscinosis, and febrile infection-related epilepsy syndrome is reviewed. Expand
EPILEPSY IN ADULTS: RESULTS OF TREATMENT BY KETOGENIC DIET IN ONE HUNDRED CASES
TLDR
The use of diets high in fat and extremely low in carbohydrate in the treatment for idiopathic epilepsy was first suggested by Wilder as a possible substitute for the fasting regimen which had previously been shown by Guelpa and Marie 2 and by Geyelin 3 to influence seizures in many cases. Expand
KETOGENIC DIETS IN THE TREATMENT OF EPILEPSY: SHORT‐TERM CLINICAL EFFECTS
TLDR
The three ketogenic diets were shown to be effective in the short‐term management of children whose epilepsy is poorly controlled with anticonvulsant drugs. Expand
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