Ketogenic diet modifies the gut microbiota in a murine model of autism spectrum disorder

@inproceedings{Newell2016KetogenicDM,
  title={Ketogenic diet modifies the gut microbiota in a murine model of autism spectrum disorder},
  author={Christopher Newell and Marc R Bomhof and Raylene A Reimer and Dustin S. Hittel and Jong M. Rho and Jane Shearer},
  booktitle={Molecular autism},
  year={2016}
}
BACKGROUND Gastrointestinal dysfunction and gut microbial composition disturbances have been widely reported in autism spectrum disorder (ASD). This study examines whether gut microbiome disturbances are present in the BTBR(T + tf/j) (BTBR) mouse model of ASD and if the ketogenic diet, a diet previously shown to elicit therapeutic benefit in this mouse model, is capable of altering the profile. FINDINGS Juvenile male C57BL/6 (B6) and BTBR mice were fed a standard chow (CH, 13 % kcal fat) or… CONTINUE READING
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