Ketogenic Diets: An Update for Child Neurologists

@article{Kossoff2009KetogenicDA,
  title={Ketogenic Diets: An Update for Child Neurologists},
  author={Eric H. Kossoff and Beth A Zupec-Kania and Jong M. Rho},
  journal={Journal of Child Neurology},
  year={2009},
  volume={24},
  pages={979 - 988}
}
The ketogenic diet, modified Atkins diet, and low-glycemic-index treatment have all emerged over the past decade as important therapeutic options for children with intractable epilepsy. Whereas only a decade ago the ketogenic diet was seen as an ``alternative'' treatment of last resort, it has become more frequently used throughout the world. The past year alone 2 randomized and controlled trials of the ketogenic diet were published, as well as the use of the ketogenic diet for new-onset… 
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156 Citations
Highly Influential Citations
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Background Citations
66
Methods Citations
6
Results Citations
2

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156 Citations

The ketogenic diet and other dietary treatments for refractory epilepsy in children
TLDR
The ketogenic diet is a high-fat, low-carbohydrate, and restricted protein diet that is useful in patients with refractory epilepsy and other modifications of the diet are also beneficial, such as the modified Atkins diet and the low glycemic index treatment.
The Ketogenic Diet: A Practical Guide for Pediatricians.
TLDR
The proposed mechanisms of a ketogenic diet's antiseizure action, its clinical indications, and its contraindications are discussed, and the steps involved inketogenic diet initiation, monitoring, and management of its side effects are discussed.
Ketogenic diet practices on childhood epilepsies
TLDR
The mechanism of neuroprotective action of KD, clinical indications and contraindications will be discussed, and general pediatricians will be able to provide advice to the child’s family and caregivers by increasing the skills they need to know about the care of children using KD.
An Update on the Ketogenic Diet, 2012
TLDR
Although most neurologists do not consider it as being the preferred first-line therapy, it is often a reasonable option when two medications have already failed, and validating its application in severe epilepsies in infancy, such as infantile spasms is valid.
The use of ketogenic diet in special situations: expanding use in intractable epilepsy and other neurologic disorders
  • Munhyang Lee
  • Medicine, Psychology
    Korean journal of pediatrics
  • 2012
TLDR
An overview about the expanding use and emerging trials of the ketogenic diet in various neurologic disorders excluding intractable epilepsy is introduced and explanations of the mechanisms in that usage are provided.
Ketogenic diet for infants with epilepsy: A literature review
The Use of Ketogenic Diet in Pediatric Patients with Epilepsy
TLDR
Patients on ketogenic diets who exceed their daily carbohydrate limit have the risk of seizure relapse, necessitating hospital readmission to repeat the diet initiation process, and are at a high risk for diversion from the diet.
Ketogenic Diet and Epilepsy: The Role of Adenosine
TLDR
Current research on mechanism(s) of KD action is highlighted, with a focus on adenosine, and the concept that the KD is both an accessible and affordable therapy is promoted by describing an international case study of recent KD training and initial outcomes in the Republic of Georgia.
The use of a formula-based ketogenic diet in children with refractory epilepsy.
TLDR
The ketogenic formula tested herein caused only mild KD-related adverse events and adequate adherence, and 60% of patients had more than 50% seizure frequency reduction and 10% were seizure-free.
Dietary treatment of epilepsy: rebirth of an ancient treatment.
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