Ketogenesis from butyrate and acetate by the caecum and the colon of rabbits.

  title={Ketogenesis from butyrate and acetate by the caecum and the colon of rabbits.},
  author={Sudan J Henning and F J Hird},
  journal={The Biochemical journal},
  volume={130 3},
1. When studied in vitro, tissue from the caecum and the proximal colon of rabbits converted butyrate into ketone bodies. The conversion was similar to that observed with liver slices. The ketogenic activity was associated with the mucosa rather than the muscle of the gut wall and, in the colon, diminished as the distance from the caecal-colonic junction increased. 2. Tissue from the wall of the ileum, caecum, proximal colon and distal colon was also shown to metabolize [1-(14)C]butyrate to… CONTINUE READING
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