Ketoconazole ion-exchange fiber complex: a novel method to reduce the individual difference of bioavailability in oral administration caused by gastric anacidity.

@article{Xin2013KetoconazoleIF,
  title={Ketoconazole ion-exchange fiber complex: a novel method to reduce the individual difference of bioavailability in oral administration caused by gastric anacidity.},
  author={Che Xin and Wang Li-hong and Yuan Jing and Yang Yang and Yuan Yue and Wang Qi-fang and Li San-ming},
  journal={Pharmaceutical development and technology},
  year={2013},
  volume={18 6},
  pages={1346-54}
}
Water insoluble faintly alkaline drugs often have potential absorption problem in gastrointestinal tract in oral administration for patients with gastric anacidity. The purpose of the present study is to develop a novel method to improve the absorption of the water insoluble faintly alkaline drug in peroral administration. This method is based on ion… CONTINUE READING