Ketamine use: a review.

  title={Ketamine use: a review.},
  author={Celia J. A. Morgan and H. Valerie Curran},
  volume={107 1},
AIMS Ketamine remains an important medicine in both specialist anaesthesia and aspects of pain management. [] Key MethodMETHOD The literature on ketamine was systematically searched and findings were classified into the matrix of Nutt et al.'s (2007) rational scale for assessing the harms of psychoactive substances. RESULTS A major physical harm is ketamine induced ulcerative cystitis which, although its aetiology is unclear, seems particularly associated with chronic, frequent use of the drug. Frequent…

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This review will serve to touch on ketamine's chemical data, pharmacokinetics and pharmacodynamics, medical uses, and adverse effects while focusing specifically on the drugs usage in anesthesia and analgesia.
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Chapter 12 – Ketamine


A Review of the Nonmedical Use of Ketamine: Use, Users and Consequences
  • K. Jansen
  • Psychology
    Journal of psychoactive drugs
  • 2000
The history of ketamine, its growing role as a “dance drug,” the sought-after effects for which it is taken in a nonmedical context, how these are produced, common mental and physical adverse effects, and the ketamine model of schizophrenia are reviewed.
[A case of ketamine dependence].
The authors describe the case of a 52 year old man who has been addicted to ketamine for 15 years and was admitted to hospital to observe and treat the withdrawal syndrome as an effect of abrupt discontinuation of a chronically abused substance.
Wherefore ketamine?
  • J. Persson
  • Medicine
    Current opinion in anaesthesiology
  • 2010
Purpose of review Ketamine has been repeatedly reviewed in this journal but novel developments have occurred in the last few years prompting an update. Interesting recent publications will be
Ketamine associated psychedelic effects and dependence.
  • D. Lim
  • Psychology, Medicine
    Singapore medical journal
  • 2003
The psychedelic and psychotic effects of ketamine were dose-related and comprised multimodal hallucinatory experiences, a sense of slowing, paranoid ideation and enhancement of sexual, musical and sensory enjoyment in two ketamine dependent patients who have presented to the psychiatric service.
Ketamine psychedelic therapy (KPT): a review of the results of ten years of research.
A considerable increase in efficacy of the authors' standard alcoholism treatment when supplemented by ketamine psychedelic therapy (KPT) is demonstrated, and these psychological changes were shown to favor a sober lifestyle.
Ketamine use, cognition and psychological wellbeing: a comparison of frequent, infrequent and ex-users with polydrug and non-using controls.
Frequent ketamine use is associated with impairments in working memory, episodic memory and aspects of executive function as well as reduced psychological wellbeing.
Pharmacological Aspects and Potential New Clinical Applications of Ketamine: Reevaluation of an Old Drug
Reevaluation, though, of analgesic properties of ketamine resulted in new interest regarding its use in perioperative and chronic pain management and recent studies in the effects of the substance on intracranial pressure and cerebral blood flow led to revising the recommendation against itsUse in brain injury.
Consequences of chronic ketamine self-administration upon neurocognitive function and psychological wellbeing: a 1-year longitudinal study.
Findings imply that heavy use of ketamine is harmful to aspects of both cognitive function and psychological wellbeing.
Ketamine Case Study: The Phenomenology of a Ketamine Experience
Psychonautics refers both to a methodology for describing and explaining the subjective effects of drugs, and to a long established research paradigm in which intellectuals have taken drugs to