Ketamine stereoselectively inhibits rat dopamine transporter

@article{Nishimura1999KetamineSI,
  title={Ketamine stereoselectively inhibits rat dopamine transporter},
  author={M. Nishimura and K. Sato},
  journal={Neuroscience Letters},
  year={1999},
  volume={274},
  pages={131-134}
}
Ketamine is usually administered as a racemate, which is composed of the two isomers, S(+)-and R(-)-ketamine. Recently, we have shown that racemic ketamine at clinical relevant concentrations specifically inhibits the transporter proteins for norepinephrine, dopamine and serotonin heterologously expressed in HEK-293 cells (Nishimura, M., Sato, K., Okada, T., Yoshiya, I., Schloss, P., Shimada, S. and Tohyama, M., Ketamine inhibits monoamine transporters expressed in human embryonic kidney 293… Expand
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