Ketamine increases the frequency of electroencephalographic bicoherence peak on the alpha spindle area induced with propofol.

@article{Hayashi2007KetamineIT,
  title={Ketamine increases the frequency of electroencephalographic bicoherence peak on the alpha spindle area induced with propofol.},
  author={K. Hayashi and N Tsuda and Teiji Sawa and Satoshi Hagihira},
  journal={British journal of anaesthesia},
  year={2007},
  volume={99 3},
  pages={
          389-95
        }
}
BACKGROUND The reticular and thalamocortical system is known to play a prominent role in spindle wave activity, and the spindle wave is related to the sedative effects of anaesthetics. Recently, bispectral analysis of the EEG has been developed as a better method to indicate nonlinear regulation including the thalamocortical system linking to the cortical area. In the present study, in order to explore the interference of ketamine with the nonlinear regulation of the sub-cortical system, we… 
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