Ketamine for suicidal ideation in adults with psychiatric disorders: A systematic review and meta-analysis of treatment trials

  title={Ketamine for suicidal ideation in adults with psychiatric disorders: A systematic review and meta-analysis of treatment trials},
  author={Katrina G. Witt and Jennifer Potts and Anna A M Hubers and Michael F. Grunebaum and James W. Murrough and Colleen K. Loo and Andrea Cipriani and Keith Hawton},
  journal={Australian \& New Zealand Journal of Psychiatry},
  pages={29 - 45}
  • K. Witt, J. Potts, K. Hawton
  • Published 15 November 2019
  • Psychology, Medicine
  • Australian & New Zealand Journal of Psychiatry
Objective: Ketamine may reduce suicidal ideation in treatment-resistant depression. But it is not known how quickly this occurs and how long it persists. We undertook a systematic review and meta-analysis to determine the short- and long-term effectiveness of ketamine for suicidality. Method: CENTRAL, EMBASE, Medline, and PsycINFO were searched until 12 December 2018. Randomised controlled trials of ketamine or esketamine reporting data on suicidal ideation, self-harm, attempted or completed… 

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