Ketamine for acute neuropathic pain in patients with spinal cord injury

  title={Ketamine for acute neuropathic pain in patients with spinal cord injury},
  author={Kyongsong Kim and Masahiro Mishina and Rinko Kokubo and Takao Nakajima and Akira Teramoto},
  journal={Journal of Clinical Neuroscience},
Ketamine, an N-methyl-d-aspartic acid (NMDA) receptor antagonist, may be useful for treating neuropathic pain, which is often difficult to control. We report a prospective study of 13 patients with acute neuropathic pain due to spinal cord injury (SCI) treated with ketamine. All underwent a test challenge with 5mg ketamine. Patients with satisfactory responses were then treated intravenously and subsequently perorally with ketamine. Pre- and post-treatment pain was recorded on a visual analogue… CONTINUE READING

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