Ketamine administration in depressive disorders: a systematic review and meta-analysis

  title={Ketamine administration in depressive disorders: a systematic review and meta-analysis},
  author={Guillaume Fond and Anderson Dieudonn{\'e} Loundou and Corentin Rabu and Alexandra Macgregor and Christophe Lançon and Marie Brittner and Jean-Arthur Micoulaud-Franchi and Raphaelle Richieri and Philippe Courtet and Mocrane Abbar and Matthieu Roger and Marion Leboyer and Laurent Boyer},
Ketamine’s efficacy in depressive disorders has been established in several controlled trials. The aim of the present study was to determine whether or not ketamine administration significantly improves depressive symptomatology in depression and more specifically in major depressive disorder (MDD), bipolar depression, resistant depression (non-ECT studies), and as an anesthetic agent in electroconvulsive therapy (ECT) for resistant depression (ECT studies). Secondary outcomes were the duration… CONTINUE READING
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