Ketamine Treatment and Global Brain Connectivity in Major Depression

  title={Ketamine Treatment and Global Brain Connectivity in Major Depression},
  author={Chadi G. Abdallah and Lynnette A. Averill and Katherine A Collins and Paul Y. Geha and Jaclyn Schwartz and Christopher L. Averill and Kaitlin E Dewilde and Edmund W Wong and Alan Anticevic and Cheuk Y. Tang and Dan V. Iosifescu and Dennis S. Charney and James W. Murrough},
Capitalizing on recent advances in resting-state functional connectivity magnetic resonance imaging (rs-fcMRI) and the distinctive paradigm of rapid mood normalization following ketamine treatment, the current study investigated intrinsic brain networks in major depressive disorder (MDD) during a depressive episode and following treatment with ketamine. Medication-free patients with MDD and healthy control subjects (HC) completed baseline rs-fcMRI. MDD patients received a single infusion of… CONTINUE READING
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