Ketamine Inhibits Monoamine Transporters Expressed in Human Embryonic Kidney 293 Cells

@article{Nishimura1998KetamineIM,
  title={Ketamine Inhibits Monoamine Transporters Expressed in Human Embryonic Kidney 293 Cells},
  author={Mitsuhiro Nishimura and Kohji Sato and T. Okada and Ikuto Yoshiya and Patrick Schloss and S Shimada and Masaya Tohyama},
  journal={Anesthesiology},
  year={1998},
  volume={88},
  pages={768–774}
}
Background Ketamine has been characterized as having psychotomimetic and sympathomimetic effects. These symptoms have raised the possibility that ketamine affects monoaminergic neurotransmission. To elucidate the relation between ketamine and monoamine transporters, the authors constructed three cell lines that stably express the norepinephrine, dopamine, and serotonin transporters and investigated the effects of ketamine on these transporters. Methods Human embryonic kidney cells were… Expand
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