Ketamine Analog Methoxetamine Induced Inflammation and Dysfunction of Bladder in Rats

@inproceedings{Wang2017KetamineAM,
  title={Ketamine Analog Methoxetamine Induced Inflammation and Dysfunction of Bladder in Rats},
  author={Qiang Wang and Qinghui Wu and Junpeng Wang and Yang Chen and Guihao Zhang and Jiawei Chen and Jie Zhao and Peng Wu},
  booktitle={International journal of molecular sciences},
  year={2017}
}
The novel synthetic psychoactive ketamine analog methoxetamine is reportedly being used for recreational purposes. As ketamine use can result in urinary dysfunction, we conducted the present study to investigate how methoxetamine affects the bladder. A cystometry investigation showed that female Sprague-Dawley rats experienced increased micturition frequency bladder dysfunction after receiving a daily intraperitoneal injection of 30 mg/kg methoxetamine or ketamine for periods of 4 or 12 weeks… CONTINUE READING

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