Keratopathy in pseudoexfoliation syndrome as a cause of corneal endothelial decompensation: a clinicopathologic study.

@article{Naumann2000KeratopathyIP,
  title={Keratopathy in pseudoexfoliation syndrome as a cause of corneal endothelial decompensation: a clinicopathologic study.},
  author={Gottfried O. H. Naumann and Ursula Schl{\"o}tzer-Schrehardt},
  journal={Ophthalmology},
  year={2000},
  volume={107 6},
  pages={
          1111-24
        }
}
Quantitative and qualitative corneal endothelial morphology of omani patients with pseudoexfoliation syndrome.
TLDR
It is revealed that corneal decompensation in PEX eyes can occur in presence of abnormalities in polymegathism and pleomorphism, even when the endothelial cell counts may be normal.
In vivo confocal microscopic evidence of keratopathy in patients with pseudoexfoliation syndrome.
TLDR
Corneal sensitivity was significantly decreased in PEX eyes, and this was significantly correlated with the decrease of basal epithelial cell and subbasal nerve densities, which shed light on understanding of the pathogenesis of decreased cornealensitivity.
Characteristics of the cornea in patients with pseudoexfoliation syndrome.
TLDR
Eyes with PEX presented decreased corneal sub-basal nerve plexus variables and cell densities in all corneas, except for the mean basal epithelial cell density.
In vivo confocal microscopic and histological findings of unknown bullous keratopathy probably associated with pseudoexfoliation syndrome
TLDR
The findings suggest that the BK was caused by the corneal endotheliopathy of PEX, a common disease that could affect up to 30% of people over 60 years old and is more prevalent than the authors have believed.
New Findings for an Old Disease: Morphological Studies on Pseudoexfoliation Syndrome–Related Keratopathy and Binocular Asymmetry
TLDR
PEX keratopathy involves all layers of the cornea and changes of the anterior chamber may contribute to PEX progression, especially in a country with a large aged population, such as Japan.
Surgical Approach to the Pseudoexfoliative Cataract
TLDR
The first step in preoperative planning for cataract extraction is to identify patients with PXF, a systemic disease characterized by the deposition of extracellular fibrillar material that is associated with an increased prevalence of lens opacification and nuclear sclerosis.
An in vivo confocal microscopy study of corneal changes in pseudoexfoliation syndrome
TLDR
Corneal in vivo confocal microscopy is demonstrated as a non-invasive and high-reproducible technique to evaluate pathophysiology of each corneal layer; the sub-basal nerve plexus alterations are correlated with the lower corneas of the eyes with pseudoexfoliation syndrome.
Corneal Alterations Associated with Pseudoexfoliation Syndrome and Glaucoma: A Literature Review
TLDR
Further evidence is provided of the significant negative influence PEX has on the cornea, worsening as patients convert to PEXG, and EcD and corneal nerve densities may be potential metrics for risk-stratifying patients with PEX and P EXG.
Pseudoexfoliation syndrome: pathological manifestations of relevance to intraocular surgery
TLDR
Current reports relating to PEX pathological changes of practical interest to the intraocular surgeon are summarized and patients need to be given realistic expectations regarding the increased risk of complications and more prolonged expected recovery time.
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References

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Corneal endothelial involvement in pseudoexfoliation syndrome.
TLDR
The present findings indicate that the pseudoexfoliation material is initially formed by degenerative endothelial cells and that it becomes subsequently buried by overgrowing cells in patients with pseudo exfoliation syndrome.
Corneal endothelial involvement in pseudoexfoliation syndrome.
TLDR
In one of the latest issues of theArchives, Schlotzer-Schrehardt et al claimed to provide evidence that pseudoexfoliation (PSX) material may be derived from the corneal endothelium, and observed what they called desquamating endothelial cells characterized by large quantities of phagocytosed melanin granules.
Pseudoexfoliation syndrome. Ocular manifestation of a systemic disorder?
TLDR
Findings provide evidence for the systemic nature of the pseudoexfoliation syndrome, which apparently involves an aberrant connective-tissue metabolism throughout the body.
Progressive corneal endothelial cell changes in anterior segment disease.
We have demonstrated marked changes in the corneal endothelium in some groups of patients with ocular anterior segment disease including chronic cyclitis, both heterochromic and classical,
Anterior-chamber hypoxia and iris vasculopathy in pseudoexfoliation syndrome.
TLDR
It is concluded that anterior-chamber hypoxia due to iris vasculopathy may represent a complication of PES that could play a role in the pathogenesis of P ES-associated alterations in the anterior segment of the eye.
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