Keratins and the skin.

@article{Fuchs1995KeratinsAT,
  title={Keratins and the skin.},
  author={Elaine Fuchs},
  journal={Annual review of cell and developmental biology},
  year={1995},
  volume={11},
  pages={123-53}
}
  • Elaine Fuchs
  • Published 1995 in Annual review of cell and developmental biology
Keratins are the major structural proteins of the vertebrate epidermis and its appendages, constituting up to 85% of a fully differentiated keratinocyte. Together with actin microfilaments and microtubules, keratin filaments make up the cytoskeletons of vertebrate epithelial cells. Traced as far back in the evolutionary kingdom as mollusks, keratins belong to the superfamily of intermediate filament (IF) proteins that form alpha-helical coiled-coil dimers which associate laterally and end-to… CONTINUE READING

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