Keratinocytes in inflammatory skin diseases.

  title={Keratinocytes in inflammatory skin diseases.},
  author={Cristina Albanesi and Claudia Scarponi and Maria Laura Giustizieri and Giampiero Girolomoni},
  journal={Current drug targets. Inflammation and allergy},
  volume={4 3},
Although in the past, keratinocytes were considered simply as passive targets of immunological attack from infiltrating T lymphocytes, a number of studies have definitively demonstrated that keratinocytes actively participate in the cutaneous immune responses. Upon activation, keratinocytes express a plethora of cytokines, chemokines and accessory molecules, which can transmit both positive and negative signals to cells of innate and adaptive immunity. Dysregulation and abnormal expression of… CONTINUE READING


Publications citing this paper.
Showing 1-10 of 47 extracted citations

Topical vaccination: the skin as a unique portal to adaptive immune responses

Seminars in Immunopathology • 2007
View 8 Excerpts
Highly Influenced

Skin Immunity

Archivum Immunologiae et Therapiae Experimentalis • 2017
View 4 Excerpts
Highly Influenced

Cytokine-based therapy in psoriasis.

Clinical reviews in allergy & immunology • 2013
View 14 Excerpts
Highly Influenced

Similar Papers

Loading similar papers…