Keratinocyte transglutaminase in human skin and oral mucosa: cytoplasmic localization and uncoupling of differentiation markers.

@article{Ta1990KeratinocyteTI,
  title={Keratinocyte transglutaminase in human skin and oral mucosa: cytoplasmic localization and uncoupling of differentiation markers.},
  author={Baramki Ta and George T. Gallagher and Rajtilok Chakravarty and Robert H. Rice},
  journal={Journal of cell science},
  year={1990},
  volume={95 ( Pt 4)},
  pages={
          631-8
        }
}
Expression of keratinocyte transglutaminase, a specific differentiation marker, has been examined by immunogold-silver cytochemistry in human epidermis and oral epithelium, and in oral mucosal hyperplasia and neoplasia. Two major findings have been obtained. First, considerable immunoreactivity was evident not only at the plasma membrane (the site of cross-linked envelope formation) but also in the cytoplasm of spinous cells, suggesting a cytoplasmic function for this transglutaminase. Staining… CONTINUE READING

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