Keratinocyte-specific deletion of the receptor RAGE modulates the kinetics of skin inflammation in vivo.

Abstract

The receptor for advanced glycation end products (RAGE) is a pattern recognition receptor causally related to the pathogenesis of acute and chronic inflammation. In a mouse model of inflammation-driven skin carcinogenesis, RAGE deletion conferred protection from the development of skin tumors due to a severely impaired cutaneous inflammation. Although the… (More)
DOI: 10.1038/jid.2013.185

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@article{Leibold2013KeratinocytespecificDO, title={Keratinocyte-specific deletion of the receptor RAGE modulates the kinetics of skin inflammation in vivo.}, author={Julia S Leibold and Astrid Riehl and Jan Hettinger and Michael Durben and Jochen Hess and Peter Angel}, journal={The Journal of investigative dermatology}, year={2013}, volume={133 10}, pages={2400-2406} }