Keratinocyte growth factor regulates proliferation and differentiation of hematopoietic cells expressing the receptor gene K-sam.

Abstract

OBJECTIVE The aim of this study was to establish a new method to overcome the problems of gene therapy targeting hematopoietic cells, namely low transduction efficiency and induction of differentiation during cytokine treatment. MATERIALS AND METHODS The K-sam gene encoding the receptor for keratinocyte growth factor (KGF) was transduced to three factor… (More)

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