Keratinocyte growth factor is up-regulated by estrogen in the porcine uterine endometrium and functions in trophectoderm cell proliferation and differentiation.

@article{Ka2001KeratinocyteGF,
  title={Keratinocyte growth factor is up-regulated by estrogen in the porcine uterine endometrium and functions in trophectoderm cell proliferation and differentiation.},
  author={Hakhyun Ka and Laurie A. Jaeger and Gregory A. Johnson and Thomas E Spencer and Fuller W Bazer},
  journal={Endocrinology},
  year={2001},
  volume={142 6},
  pages={2303-10}
}
Keratinocyte growth factor (KGF) is expressed by uterine endometrial epithelial cells during the estrous cycle and during pregnancy in pigs, whereas KGF receptor is expressed in conceptus trophectoderm and endometrial epithelia. In particular, KGF expression in the endometrium is highest on day 12 of pregnancy. This corresponds to the period of maternal recognition of pregnancy in pigs, which is signaled by large amounts of estrogen secreted by conceptus trophectoderm acting on the endometrium… CONTINUE READING
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