Keratinocyte apoptosis following bone marrow transplantation: evidence for CTL-dependent and -independent pathways

Abstract

Acute graft-versus-host disease (GVHD) is a complication of bone marrow transplantation (BMT). The histopathologic features used to diagnose GVHD are non-specific, and may be secondary to chemotherapy or irradiation given before BMT. The presence of apoptotic keratinocytes or activated CTL may distinguish GVHD from conditioning effects. This study… (More)
DOI: 10.1038/sj.bmt.1701344

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