Keeping the eIF2 alpha kinase Gcn2 in check.

@article{Castilho2014KeepingTE,
  title={Keeping the eIF2 alpha kinase Gcn2 in check.},
  author={B. Castilho and R. Shanmugam and Richard C. Silva and R. Ramesh and B. Himme and E. Sattlegger},
  journal={Biochimica et biophysica acta},
  year={2014},
  volume={1843 9},
  pages={
          1948-68
        }
}
The protein kinase Gcn2 is present in virtually all eukaryotes and is of increasing interest due to its involvement in a large array of crucial biological processes. Some of these are universally conserved from yeast to humans, such as coping with nutrient starvation and oxidative stress. In mammals, Gcn2 is important for e.g. long-term memory formation, feeding behaviour and immune system regulation. Gcn2 has been also implicated in diseases such as cancer and Alzheimer's disease. Studies on… Expand
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