Keeping chromatin quiet: how nucleosome remodeling restores heterochromatin after replication.

@article{Mermoud2011KeepingCQ,
  title={Keeping chromatin quiet: how nucleosome remodeling restores heterochromatin after replication.},
  author={Jacqueline E. Mermoud and Samuel P Rowbotham and Patrick D Varga-Weisz},
  journal={Cell cycle},
  year={2011},
  volume={10 23},
  pages={4017-25}
}
Disruption of chromatin organization during replication poses a major challenge to the maintenance and integrity of genome organization. It creates the need to accurately reconstruct the chromatin landscape following DNA duplication but there is little mechanistic understanding of how chromatin based modifications are restored on newly synthesized DNA. ATP-dependent chromatin remodeling activities serve multiple roles during replication and recent work underscores their requirement in the… CONTINUE READING

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