Keeping abreast of the mammary epithelial hierarchy and breast tumorigenesis.

  title={Keeping abreast of the mammary epithelial hierarchy and breast tumorigenesis.},
  author={Jane E. Visvader},
  journal={Genes & development},
  volume={23 22},
The epithelium of the mammary gland exists in a highly dynamic state, undergoing dramatic morphogenetic changes during puberty, pregnancy, lactation, and regression. The recent identification of stem and progenitor populations in mouse and human mammary tissue has provided evidence that the mammary epithelium is organized in a hierarchical manner. Characterization of these normal epithelial subtypes is an important step toward understanding which cells are predisposed to oncogenesis. This… CONTINUE READING
Highly Influential
This paper has highly influenced 15 other papers. REVIEW HIGHLY INFLUENTIAL CITATIONS
Related Discussions
This paper has been referenced on Twitter 1 time. VIEW TWEETS


Publications citing this paper.
Showing 1-10 of 258 extracted citations

Mammary gland stem cells: More puzzles than explanations

Journal of Biosciences • 2012
View 6 Excerpts
Highly Influenced


Publications referenced by this paper.
Showing 1-10 of 63 references

PML depletion disrupts normal mammary gland development and skews the composition of the mammary luminal cell progenitor pool.

Proceedings of the National Academy of Sciences of the United States of America • 2009
View 2 Excerpts

Similar Papers

Loading similar papers…