Kayser-Fleischer ring and associated cataract in Wilson's disease.

  title={Kayser-Fleischer ring and associated cataract in Wilson's disease.},
  author={Mark O. M. Tso and Ben S. Fine and H E Thorpe},
  journal={American journal of ophthalmology},
  volume={79 3},
A 22-year-old woman with hepatolenticular degeneration, or Wilson's disease, was note clinically to have Kayser-Fleischer rings and associated cataracts. Histopathologic, histochemical, and electron microscopic study of the cornea showed deposition of copper in the peripheral Descemet's membrane, with excessive accumulation in Hassall-Henel warts. Copper deposits were also noted in the anterior and posterior lens capsule without the presence of degenerative changes in the epithelial or cortical… CONTINUE READING