Kawasaki disease with lymphadenopathy and fever as sole initial manifestations

@article{Kubota2008KawasakiDW,
  title={Kawasaki disease with lymphadenopathy and fever as sole initial manifestations},
  author={Masaru Kubota and Ikuya Usami and Masaru Yamakawa and Yasuhiko Tomita and Tsunekazu Haruta},
  journal={Journal of Paediatrics and Child Health},
  year={2008},
  volume={44}
}
Aim:  Initial presentation with only cervical lymphadenopathy and fever is one of the pitfalls in the diagnosis of Kawasaki disease (KD). As the number of such patients is small, their clinical features have remained uncertain. The purpose of the present study is to characterise the features of such KD patients, especially in comparison with those of patients with common onset. 
Kawasaki Disease with Fever and Cervical Lymphadenopathy as the Sole Initial Presentation
TLDR
Even though LKD patients were older, admitted earlier, and had higher inflammatory marker levels, they did not have a greater risk of CALs or IVIG resistance, and echocardiography may be helpful in the acute stage if patients have only fever and cervical lymphadenopathy and are unresponsive to empirical antibiotics.
Kawasaki Shock Syndrome with Initial Presentation as Neck lymphadenitis: A Case Report
Kawasaki disease (KD) is an acute systemic vasculitis of unknown cause that mainly affects infants and children and can result in coronary artery complications if left untreated. A small subset of KD
Lymphadenitis and Fever: First Presentation of Kawasaki Disease
TLDR
An unusual case of Kawasaki disease is reported: a 3.5-yearold boy who presented with fever and bilateral cervical lymphadenitis as initial manifestations, leading to serious cardiac sequelae.
A severe form of Kawasaki disease presenting with only fever and cervical lymphadenopathy at admission.
TLDR
KDiL indicates a severe form of KD associated with increased risks of additional intravenous immunoglobulin treatment and coronary artery abnormalities and patients with KDiL may require heightened surveillance and more aggressive treatment.
Comparison between Kawasaki disease with lymph-node-first presentation and Kawasaki disease without cervical lymphadenopathy
TLDR
KD should be suspected in children who are unresponsive to antibiotics and have prolonged fever and cervical lymphadenopathy, which indicates that KD is associated with the likelihood of requiring second-line treatment and risk of developing coronary artery dilatation.
Kawasaki disease: characteristics, diagnosis, and unusual presentations
TLDR
Although 2D echocardiography continues to be the preferred imaging modality for cardiac assessment in patients with KD, it has its limitations.
Kawasaki Disease: Clinical and Epidemiological Characteristics of Our Cases
TLDR
Coronary artery involvement is more common in this country and atypical manifestations, such as purulent conjunctivitis and suppurative lymphadenitis, may be encountered and can be difficult to distinguish.
Understanding Kawasaki Disease on the Ground of Pediatric Growth and Lymphoid Tissue Maturation
  • J. Oh
  • Medicine
    Korean circulation journal
  • 2017
TLDR
The clinical characteristics of a subgroup of KD patients showed that this KD subgroup initially presented with only cervical lymphadenopathy (lymphadenopathy-KD [LKD] group), and the LKD group showed typical diagnostic criteria of KD later during the febrile period.
Diagnostic Applications for Clinical and Imaging Data in Kawasaki Disease with Lymphadenopathy-First-Presentation
  • J. Son
  • Medicine
    Journal of cardiovascular imaging
  • 2018
TLDR
A delayed diagnosis of KD is an apparent risk factor for CAA, but whether LKD patients have a greater risk of CAA or intravenous immunoglobulin unresponsiveness is still debated.
Age-related Differences in the Course of the Acute Phase Symptoms of Kawasaki Disease
TLDR
A high index of suspicion for KD is required in febrile patients presenting with rash and in those >24 months with cervical lymphadenopathy, which often remains the only manifestation for more than a few days and complicates the diagnosis.
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Aim:  The diagnosis of Kawasaki disease (KD) in those outside the typical age range (6 months−4 years) is often delayed, potentially worsening prognosis. The features of KD in children ≤6 months and
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TLDR
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