Kava hepatotoxicity: a European view.

  title={Kava hepatotoxicity: a European view.},
  author={Rolf Teschke and Alexander Schwarzenboeck and Ahmet Tolgay Akinci},
  journal={The New Zealand medical journal},
  volume={121 1283},
Kava was well tolerated and considered as devoid of major side effects only until 1998 when the first report of assumed kava hepatotoxicity appeared. Causality of hepatotoxicity for kava +/- comedicated drugs was evident after the use of predominantly ethanolic and acetonic kava extracts in Germany (n=7), Switzerland (n=2), United States (n=1), and Australia (n=1) as well as after aqueous extracts in New Caledonia (n=2). Compliance regarding the recommendation for daily kava dose and duration… CONTINUE READING

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