Kava: A Comprehensive Review of Efficacy, Safety, and Psychopharmacology
@article{Sarris2011KavaAC, title={Kava: A Comprehensive Review of Efficacy, Safety, and Psychopharmacology}, author={Jerome Sarris and E Laporte and Isaac Schweitzer}, journal={Australian and New Zealand Journal of Psychiatry}, year={2011}, volume={45}, pages={27 - 35} }
Overview: Kava (Piper methysticum) is a South Pacific psychotropic plant medicine that has anxiolytic activity. This effect is achieved from modulation of GABA activity via alteration of lipid membrane structure and sodium channel function, monoamine oxidase B inhibition, and noradrenaline and dopamine re-uptake inhibition. Kava is available over the counter in jurisdictions such as the USA, Australia and New Zealand. Due to this, a review of efficacy, safety and clinical recommendations is…
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