Katanin maintains meiotic metaphase chromosome alignment and spindle structure in vivo and has multiple effects on microtubules in vitro

@inproceedings{McNally2014KataninMM,
  title={Katanin maintains meiotic metaphase chromosome alignment and spindle structure in vivo and has multiple effects on microtubules in vitro},
  author={Karen Perry McNally and Evan Berg and Daniel Benjamin Cortes and Veronica Quintero Hernandez and Paul E Mains and Francis J McNally},
  booktitle={Molecular biology of the cell},
  year={2014}
}
Assembly of Caenorhabditis elegans female meiotic spindles requires both MEI-1 and MEI-2 subunits of the microtubule-severing ATPase katanin. Strong loss-of-function mutants assemble apolar intersecting microtubule arrays, whereas weaker mutants assemble bipolar meiotic spindles that are longer than wild type. To determine whether katanin is also required for spindle maintenance, we monitored metaphase I spindles after a fast-acting mei-1(ts) mutant was shifted to a nonpermissive temperature… CONTINUE READING
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  • WormBook : the online review of C. elegans biology
  • 2018
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References

Publications referenced by this paper.
SHOWING 1-10 OF 35 REFERENCES

Severing at sites of microtubule crossover contributes to microtubule alignment in cortical arrays.

  • The Plant journal : for cell and molecular biology
  • 2007
VIEW 6 EXCERPTS
HIGHLY INFLUENTIAL

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