Karyotyping of comparative genomic hybridization human metaphases using kernel nearest-neighbor algorithm.

@article{Yu2002KaryotypingOC,
  title={Karyotyping of comparative genomic hybridization human metaphases using kernel nearest-neighbor algorithm.},
  author={Kai Yu and Liang Ji},
  journal={Cytometry},
  year={2002},
  volume={48 4},
  pages={
          202-8
        }
}
BACKGROUND Comparative genomic hybridization (CGH) is a relatively new molecular cytogenetic method that detects chromosomal imbalances. Automatic karyotyping is an important step in CGH analysis because the precise position of the chromosome abnormality must be located and manual karyotyping is tedious and time-consuming. In the past, computer-aided karyotyping was done by using the 4',6-diamidino-2-phenylindole, dihydrochloride (DAPI)-inverse images, which required complex image enhancement… CONTINUE READING
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