Karyotypic characterization of colorectal adenocarcinomas.

  title={Karyotypic characterization of colorectal adenocarcinomas.},
  author={Georgia Bardi and Tatyana Sukhikh and Nikos Pandis and Claus Fenger and Ole Kronborg and Sverre Heim},
  journal={Genes, chromosomes & cancer},
  volume={12 2},
Cytogenetic analysis of short-term cultures from 52 primary colorectal adenocarcinomas revealed clonal chromosome aberrations in 45 tumors, whereas the remaining 7 had a normal karyotype. More than 1 abnormal clone was detected in 26 tumors; in 18 of them, the clones were cytogenetically unrelated. The modal chromosome number was near-diploid in 32 tumors and near-triploid to near-tetraploid in 13. Only numerical aberrations were identified in 13 carcinomas, only structural aberrations in 3… CONTINUE READING
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