Karyotypic aberrations of chromosomes 16 and 17 are related to survival in patients with breast cancer.

@article{Hislop2002KaryotypicAO,
  title={Karyotypic aberrations of chromosomes 16 and 17 are related to survival in patients with breast cancer.},
  author={Robert G Hislop and Norman Pratt and Stefan Stocks and Catherine M. Steel and Milton Sales and David Goudie and Andrea Robertson and Ann M Thompson},
  journal={The British journal of surgery},
  year={2002},
  volume={89 12},
  pages={1581-6}
}
BACKGROUND Breast cancer has a high incidence and associated mortality rate, yet little is known of the sequence of genetic events that underlie the clinical course. METHODS The study was a comparative genomic hybridization analysis of 40 primary breast cancers with survival data at a mean of 8.4 years. RESULTS The mean number of aberrations was 9.0, with a mean of 5.5 gains and 3.5 deletions per tumour. The most common aberrations were: gain of 1q (27 of 40), 8q (19 of 40) and 17q (13 of… CONTINUE READING

From This Paper

Topics from this paper.
10 Citations
0 References
Similar Papers

Citations

Publications citing this paper.
Showing 1-10 of 10 extracted citations

Similar Papers

Loading similar papers…