Karyotype is prognostically more important than the FAB system's distinction between myelodysplastic syndrome and acute myelogenous leukemia.

@article{Estey1987KaryotypeIP,
  title={Karyotype is prognostically more important than the FAB system's distinction between myelodysplastic syndrome and acute myelogenous leukemia.},
  author={Elihu Estey and Michael J Keating and Dennis Dixon and Jose Maria Trujillo and Kenneth B. McCredie and Emil J. Freireich},
  journal={Hematologic pathology},
  year={1987},
  volume={1 4},
  pages={203-8}
}
Patients with myelodysplastic syndrome (MDS) and patients with acute myelogenous leukemia (AML) share certain specific karyotypes. Therefore, we compared the relative importance of karyotype and morphology (MDS vs. AML) in determining survival in these patients. We analyzed 768 patients with a banded karyotype who presented as either MDS or AML. Patients with "unfavorable" karyotypes had similarly short survivals regardless of whether they were classified as refractory anemia with excess blasts… CONTINUE READING

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Relapse after Allogeneic Hematopoietic Cell Transplantation for Myelodysplastic Syndromes: Analysis of Late Relapse Using Comparative Karyotype and Chromosome Genome Array Testing.

Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation • 2015
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Highly Influenced

Acute Myelogenous Leukemia

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2017
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Genomics-driven oncology: framework for an emerging paradigm.

Journal of clinical oncology : official journal of the American Society of Clinical Oncology • 2013

Acute myeloid leukemia.

Hematology. American Society of Hematology. Education Program • 2002

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