• Corpus ID: 58931863

Karakteristik dan Fungsi Marker Mikrosatelit Karakteristik dan fungsi mikrosatelit marker yang selalu berulang tidak secara jelas dapat diterangkan. Banyak sekali teori-teori yang mengemukakan akan hal tersebut. Dengan demikian dapat diduga bahwa terjadinya pengulangan tersebut selama proses replika

@inproceedings{Rasad2013KarakteristikDF,
  title={Karakteristik dan Fungsi Marker Mikrosatelit Karakteristik dan fungsi mikrosatelit marker yang selalu berulang tidak secara jelas dapat diterangkan. Banyak sekali teori-teori yang mengemukakan akan hal tersebut. Dengan demikian dapat diduga bahwa terjadinya pengulangan tersebut selama proses replika},
  author={Siti Darodjah Rasad},
  year={2013}
}
In year 1970 was found nucleotide sequence which have repeated sequence of nucleotide. with high polymorh and using PCR could be amplified. That sequenz of nucleotide called Microsatelite. Microsatelite consist of 1 – 6 repeated nucleotide, which is CA repeated as mostly a repeated DNA in the animal (Tautz and Renz, 1984). Based on difference of long and amount ofrepeated nucleotide, there are three kind of DNA satelite, midi-, miniand microsatelite (Matiat and Vergmaud, 1982). Microsatelite… 

References

SHOWING 1-10 OF 41 REFERENCES
Differentiation among Spanish sheep breeds using microsatellites
TLDR
Genetic variability at 18 microsatellites was analysed on the basis of individual genotypes in five Spanish breeds of sheep, showing a remarkable breed structure, with the highest level of clustering among members of the Spanish breeds in Latxa and the lowest in Merino sheep.
Probability of random sire exclusion using microsatellite markers for parentage verification.
TLDR
This work evaluated the use of five highly polymorphic microsatellite markers for parentage verification in 14 breeds of cattle in the UK by a statistical approach that takes in to account deviations from Hardy-Wienberg equilibrium and linkage disequilibrium for multiple loci.
Expansion of the myotonic dystrophy CTG repeat reduces expression of the flanking DMAHP gene
TLDR
DMAHP expression in myoblasts, muscle and myocardium is reduced by the DM mutation in as, and the magnitude of this effect depends on the extent of CTG repeat expansion, which supports the hypothesis that DMAHP participates in the pathophysiology of DM.
A hypervariable microsatellite revealed by in vitro amplification of a dinucleotide repeat within the cardiac muscle actin gene.
TLDR
Using the polymerase chain reaction to amplify a (TG)n microsatellite in the human cardiac actin gene, 12 different allelic fragments in 37 unrelated individuals were detected, 32 of whom were heterozygous and Codominant Mendelian inheritance of fragments was observed in three families with a total of 24 children.
Abundant class of human DNA polymorphisms which can be typed using the polymerase chain reaction.
TLDR
It is reported that specific human (dC-dA)n.(dG-dT)n blocks are polymorphic in length among individuals and therefore represent a vast new pool of potential genetic markers.
Trinucleotide repeat expansion at the myotonic dystrophy locus reduces expression of DMAHP
TLDR
It is demonstrated that CTG-repeat expansions can suppress local gene expression and implicate DMAHP in DM pathogenesis by showing a two- to fourfold reduction in steady-state D MAHP transcript levels relative to wild-type controls.
Genetic variation within the Merino sheep breed: analysis of closely related populations using microsatellites.
TLDR
The dendrograms constructed on the basis of microsatellite allelic frequencies showed that populations that have shared selection criteria (meat vs. wool) tend to cluster together, indicating that microsatellites are able to track relatively recent changes in the population structure of sheep breeds.
A genetic study of four Belgian pig populations by means of seven microsatellite loci
TLDR
Investigation of genetic variability within four Belgian pig breeds was investigated using seven microsatellite loci revealed a variability, decreasing in the order LW, BN, BL, and P.
Validation of microsatellite markers for routine horse parentage testing.
A parallel testing of 4803 routine Quarter Horse parentage cases, using 15 loci of blood group and protein polymorphisms (blood typing) and 11 loci of dinucleotide repeat microsatellites (DNA
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