Kar4p, a karyogamy-specific component of the yeast pheromone response pathway.

@article{Kurihara1996Kar4pAK,
  title={Kar4p, a karyogamy-specific component of the yeast pheromone response pathway.},
  author={Laurie Jo Kurihara and B. G. Stewart and Alison Gammie and Mark D Rose},
  journal={Molecular and cellular biology},
  year={1996},
  volume={16 8},
  pages={
          3990-4002
        }
}
Karyogamy is the process whereby two haploid nuclei fuse to form a diploid nucleus during mating in Saccharomyces cerevisiae. Here, we describe the characterization of the KAR4 gene, previously identified in a screen for new nuclear fusion-defective mutants. During mating, kar4 mutants were defective for the microtubule-dependent movement of nuclei, a phenotype identical to that of mutations in KAR3 and CIK1. Consistent with its mutant phenotype, we found that the kar4 mutation resulted in… CONTINUE READING
23 Citations
0 References
Similar Papers

Citations

Publications citing this paper.
Showing 1-10 of 23 extracted citations

Similar Papers

Loading similar papers…